neurofibroma

A large plexiform neurofibroma in the leg of a 6-year old male.

A neurofibroma may arise at any point along a peripheral nerve.

A neurofibroma is a lesion of the peripheral nervous system.

As of 2002, the primary treatment option for plexiform neurofibroma was surgery.

The surgeons had discovered two tumours called neurofibroma, one on each side of Mae's brain.

He had a facial tumor called a neurofibroma caused by a genetic disorder.

The neurofibroma was removed and the patient's mitral valve had to be replaced.

However, despite increased numbers of nonmyelinating Schwann cells, there is no neurofibroma yet.

As it appears that these elements are needed for neurofibroma formation, prevention or reduction could prove an effective treatment.

Plexiform neurofibroma are more difficult to treat and can transform into malignant tumors.

Plexiform neurofibroma can cause pain, disfigurement, neurological and other clinical deficits.

There has even been a documented case of a Schwannoma being induced from a neurofibroma due to radiation therapy.

Dermal neurofibroma typically arise in the teenage years and are often associated with the onset of puberty.

No meningioma or neurofibroma; in other words, there're no metastatic tumors along my spine.

A neurofibroma on the left ventricle.

A 14-year-old girl with NF1 was diagnosed with a neurofibroma involving her bladder, a rare location.

Once a plexiform neurofibroma has undergone malignant transformation, radiation and chemotherapy can be used as treatment.

In this case, the neurofibroma occurred on the face, resulting in the loss of sight in one eye and having to have it removed.

A plexiform neurofibroma has a lifetime risk of 8-12% of transformation into a malignant tumor.

Dermal neurofibroma do not become malignant.

In vitro, Tranilast, inhibits growth of neurofibroma cells.

Neurofibroma conditions are progressive and include:

In order for the neurofibroma to develop, cells that are heterozygous for the NF1 gene must be recruited to the site.

When a plexiform neurofibroma manifests on a leg or arm, it will cause extra blood circulation, and may thus accelerate the growth of the limb.

Dermal neurofibroma, manifested as single or multiple firm, rubbery bumps of varying sizes on a person's skin.