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In ophthalmology, scanning laser polarimetry utilises the birefringence of the optic nerve fibre layer to indirectly quantify its thickness, which is of use in the assessment and monitoring of glaucoma.
For example fundus photography can monitor nerve fiber layer swelling.
Firstly, this instrument is used to measure thickness of nerve fiber layer in our retina.
However, attacks may lead to permanent axonal loss and thinning of the retinal nerve fiber layer.
Optical coherence tomography can be used for more detailed study of retinal nerve fiber layer thickness.
For those with visual field defects optical coherence tomography has been recommended for follow up of nerve fiber layer thickness.
A cherry-red spot in macula may be seen, along with cotton-wool spots elsewhere, due to retinal nerve fiber layer hemorrhages.
They are caused by damage to nerve fibers and are a result of accumulations of axoplasmic material within the nerve fiber layer.
Disruption of the normal radial NFL arrangement with grayish opacity accentuating nerve fiber layer bundles.
It has been used to demonstrate a marked reduction in the thickness of the retinal nerve fiber layer in the quadrant corresponding to the optic pit.
This has future applications for monitoring glaucoma patients who either have changes in nerve fiber layer thickness or alterations in vasculature from damage to the retina.
Radial nerve fiber layer (NFL) without NFL tortuosity.
Scanning laser polarimetry is the use of polarised light to measure the thickness of the retinal nerve fiber layer as part of a glaucoma workup.
The retinal nerve fiber layer can be assessed with imaging techniques such as optical coherence tomography, scanning laser polarimetry, and/or scanning laser ophthalmoscopy.
They quantify the nerve fiber layer of disc and surrounding retina and statistically correlate the findings with a database of previously screened population of normals.
The GDx scanning laser measures the thickness of the retinal nerve fiber layer, which is the very first part of your eye that is damaged by glaucoma.
In 2003, vigabatrin was shown by Frisén and Malmgren to cause irreversible diffuse atrophy of the retinal nerve fiber layer in a retrospective study of 25 patients.
In the case of the retinal nerve fiber layer (RNFL), we relied on the quantitative measurements of its spectral reflectance by Knighton [ 32 ] .
An optical coherence tomography (OCT) shows some nerve fiber layer loss in most patients, suggesting the vision loss and color vision loss was secondary to optic neuropathy or neurodegeneration.
The nerve fiber layer, composed of retinal ganglion cell axons was not evident even adjacent to the scleral foramen where it is normally substantially thickened due to axon convergence on the optic nerve.
In the acute stage, lasting a few weeks, the affected eye demonstrates an edematous appearance of the nerve fiber layer especially in the arcuate bundles and enlarged or telangectatic and tortuous peripapillary vessels (microangiopathy).
The GDx nerve fiber analyzers measure the retinal nerve fiber layer (RNFL) thickness with a scanning laser polarimeter based on the birefringent properties of the RNFL.
This case is interesting because the astronaut did not have disc edema or choroidal folds, but was documented to have nerve fiber layer (NFL) thickening, globe flattening, a hyperopic shift and subjective complaints of loss of near vision.
Intracranial hypertension also induces changes at the cellular or axonal level such as the swelling of the fibers of the optic nerve that form the innermost layer of the retina (so called nerve fiber layer - NFL).
By injecting fluorescin into macaques before scanning, fluorescence adaptive optics scanning laser ophthalmoscopy (FAOSLO) can be utilized to image individual capillaries in the nerve fiber layer and determine the thickness of the nerve fiber layer itself.
The retinal nerve fiber layer (nerve fiber layer, stratum opticum, RNFL) is formed by the expansion of the fibers of the optic nerve; it is thickest near the porus opticus, gradually diminishing toward the ora serrata.