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Severe neonatal hypoglycemia was less common in insulin-treated women, but preterm delivery was more common.
Neonatal hypoglycemia, low blood glucose in the first month of life, occurs in about half of children with BWS.
Beckwith-Wiedemann syndrome is a rare hereditary condition, which may include other defects such as omphalocele, visceromegaly, gigantism or neonatal hypoglycemia.
Hypoglycemia in newborns with BWS should be managed according to standard protocols for treating neonatal hypoglycemia.
Another definition presented by Elliot et al. includes the presence of either three major features (anterior abdominal wall defect, macroglossia, or prepostnatal overgrowth) or two major plus three minor findings (ear pits, nevus flammeus, neonatal hypoglycemia, nephromegaly, or hemihyperplasia).