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Transient neonatal diabetes mellitus can also involve imprinting.
Mutations in the ZFP57 gene may be associated with transient neonatal diabetes mellitus.
Neonatal diabetes mellitus (NDM) is a monogenic form of diabetes that occurs in the first 6 months of life.
MODY2: Homozygous glucokinase deficiency causes severe congenital insulin deficiency resulting in persistent neonatal diabetes mellitus.
Transient neonatal diabetes mellitus (TNDM) is a form of diabetes mellitus presenting at birth that is not permanent.
In about half of those with NDM, the condition is lifelong and is called permanent neonatal diabetes mellitus (PNDM).
Overexpression of HYMAI and the protein-coding gene PLAG1 causes transient neonatal diabetes mellitus type 1 (TNDM1).
In the rest of those with NDM, the condition is transient and disappears during infancy but can reappear later in life; this type of NDM is called transient neonatal diabetes mellitus (TNDM).