myxomatous degeneration

Myxomatous degeneration is the most common cause of pure mitral valve insufficiency.

Myxomatous degeneration refers to a pathological weakening of connective tissue.

Myxomatous degeneration of the mitral valve is more common in females, and is more common in advancing age.

The Myxo ring, developed jointly with Edwards Lifesciences, has been used in treating myxomatous degeneration of the heart valves.

The most common cause of mitral regurgitation is mitral valve prolapse (MVP), which in turn is caused by myxomatous degeneration.

The most common cause of primary mitral regurgitation in the United States (causing about 50% of primary mitral regurgitation) is myxomatous degeneration of the valve.

The term is most often used in the context of mitral valve prolapse, which is known more technically as "primary form of myxomatous degeneration of the mitral valve."

An excess of dermatan sulfate in the mitral valve is characteristic of myxomatous degeneration of the leaflets leading to redundancy of valve tissue and ultimately, mitral valve prolapse (into the left atrium) and insufficiency.

Mitral valve prolapse (aka primary form of myxomatous degeneration of the mitral valve aka floppy mitral valve syndrome) is a valvular heart disease characterized by the displacement of an abnormally thickened mitral valve leaflet into the left atrium during systole.