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Additional satellite lesions may appear shortly before or after the mother yaw heals.
Approximately two to four weeks after infection, the child develops a sore "mother yaw" where the organism entered the skin.
Within ninety days (but usually less than a month) of infection a painless but distinctive "mother yaw" appears, which is a painless nodule which enlarges and becomes warty in appearance.
The site of the primary lesion, often referred to as the 'mother yaw', is on the leg in the majority of cases and, like the primary sore of syphilis, is painless unless there is other bacterial infection.