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Many patients have lesions localized in only one bone (monostotic fibrous dysplasia), affecting 70-80%.
Monostotic fibrous dysplasia (or monostotic osteitis fibrosa) is a form of fibrous dysplasia where only one bone is involved.
This disorder may involve a single bone (monostotic fibrous dysplasia or Jaffe-Lichtenstein disease) or may affect multiple bones (polyostotic fibrous dysplasia).