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On the other hand, PCl can be usefully converted to its monoamide, which in turn undergoes alkylation or arylation.
A phosphoramidite (RO)PNR is a monoamide of a phosphite diester.
In industry, PABA is prepared mainly by two routes: reduction of 4-nitrobenzoic acid and the Hoffman degradation of the monoamide derived from terephthalic acid.
Thus, the two substrates of this enzyme are monoamide of a dicarboxylic acid and HO, whereas its two products are dicarboxylate and NH.