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Those who do stand a one in four chance of bearing a child with defects like misplaced ears and deformities of the brain and heart.
The infant was born in June 1983 with a cleft palate and lip, webbed hands and misplaced ears.
These defects include facial malformations, typically missing or misplaced ears, severe mental retardation and serious heart defects.
Whatever the real toll, Dr. Graham argued then that because the birth defects were so severe - missing or misplaced ears, severe mental retardation - "the benefit of the drug to the mother never outweighs the risk to the fetus."
These include an inverted funnel capped by a half-moon shape, a series of shapes resembling a skull with two misplaced ears, and a long, proboscis-like extension stretching down almost as far as the horizon line between her domain and that of the bachelors'.