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In the course of time, microwell plates underwent many modifications.
Microwell plates and automated procedures have become standard in countless laboratories.
These included small platinum spiral loops to replace pipettes, and microwell plates instead of test tubes.
A microtitre plate (spelled microtiter in the United States) or microplate or microwell plate, is a flat plate with multiple "wells" used as small test tubes.
William's medium E, fetal bovine serum (FBS), penicillin/streptomycin, fungizone (amphotericin B), gentamycin, and Nunclon microwell plates were obtained from Gibco, Paisley, Renfrewshire, Scotland.
He introduced the idea of using calibrated spiral loops for multiple serial dilution in plastic microwell plates, and coined the term 'micromethods', first published in Hungarian in 1952 and in English in 1955, for laboratory procedures carried out on a small scale.