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This entity should not be confused with the similar sounding metanephric adenoma.
Metanephric adenoma - micrographs - webpathology.com.
Metanephric adenoma mimics - allenpress.com.
The urothelial carcinoma and metanephric adenoma appeared to share few of these genes commonly regulated between the other tissue types.
Metanephric adenoma is diagnosed histologically.
The 21 samples consisted of eight normal kidneys, nine clear cell carcinomas (CC), two chromophobe carcinomas (Chr), one urothelial carcinoma and one metanephric adenoma.
Metanephric adenoma (MA)is a rare, benign tumour of the kidney, that can have a microscopic appearance similar to a nephroblastoma (Wilms tumours), or a papillary renal cell carcinoma.
Nine patients were diagnosed with clear cell carcinomas (CC), two with chromophobe cell carcinomas (Chr), one with a papillary urothelial carcinoma, and one with a metanephric adenoma.
Pathology reports on these samples revealed that these were not RCCa samples but instead patient 20 was a papillary urothelial carcinoma and the sample from patient 18 was not a carcinoma but a benign metanephric adenoma.
MA has been described in the past under other names such as néphrome néphronogène, metanephroider Nierentumor and nephroblastomartiges Nierenadenom (5) but the term metanephric adenoma was suggested by Brisigotti, Cozzutto et al. in 1992 and then widely accepted.
Post-operatively, the presence of renin granules in pathology specimens as well as immunohistochemical analyses could help differentiating this tumor from other primary renal tumors such as hemangiopericytoma, glomus tumor, metanephric adenoma, epithelioid angiomyolipoma, Wilms tumor, solitary fibrous tumor, and some epithelial neoplasms.