megakaryocyte

These are small fragments (pieces) of a cell called a megakaryocyte.

The cell eventually reaches megakaryocyte stage and loses its ability to divide.

A single megakaryocyte can give rise to thousands of thrombocytes.

An example of a cell that goes through endomitosis is the megakaryocyte.

Each of these pieces is a platelet and a single megakaryocyte can make 2,000 to 3,000 platelets.

It is a colony-stimulating factor that stimulates megakaryocyte production.

Each megakaryocyte produces between 5,000 and 10,000 platelets.

The developmental stages of the megakaryocyte are:

Once the cell has completed differentiation and become a mature megakaryocyte, it begins the process of producing platelets.

The megakaryocyte develops through the following lineage:

And to be informed that a "megakaryoblast" was simply an immature megakaryocyte was not much help at all.

You may want to research megakaryocyte if you are looking into causes and related information for a low MPV.

Beta-Thromboglobulin also affects megakaryocyte maturation, and thus helps in regulating platelet production.

A promegakaryocyte is a precursor cell for a megakaryocyte, arising from a megakaryoblast.

Thrombopoietin plays a role in inducing the megakaryocyte to form small proto-platelet processes.

Thrombopoietin stimulates megakaryopoiesis, process of megakaryocyte maturation and differentiation.

It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation.

The primary signal for megakaryocyte production is thrombopoietin or TPO.

There are several diseases which are directly attributable to abnormal megakaryocyte function or abnormal platelet function.

Thrombopoietin, upon release, binds to its receptor, c-mpl, found on megakaryocyte progenitor cells.

A megakaryoblast is a precursor cell to a promegakaryocyte, which in turn becomes a megakaryocyte during haematopoiesis.

During its maturation, the megakaryocyte grows in size and replicates its DNA without cytokinesis.

Megakaryocyte and platelet production is regulated by thrombopoietin, a hormone usually produced by the liver and kidneys.

Intriguing Possibilities Even more intriguing, the orphan receptor was found on a tumor cell that could become either a red blood cell or a megakaryocyte.

Evidence suggests this mutation renders the megakaryocyte hypersensitive to thrombopoietin and causes clonal proliferation of megakaryocytes.