mechanosensation

This has made it possible to observe and experiment with all the major stages of mechanosensation.

Many mutations that result in defective mechanosensation have been identified.

Hair cells are the source of the most detailed understanding of mechanosensation.

Both hearing and touch are types of mechanosensation.

The channel mediating human proprioceptive mechanosensation has yet to be discovered.

Piezo1 is expressed in the lungs, bladder and skin, where mechanosensation has important biological roles.

Mechanosensation is a response mechanism to mechanical stimuli.

These cilia play important roles in chemosensation, mechanosensation, and thermosensation.

States of neuropathic pain, such as hyperalgesia and allodynia, are also directly related to mechanosensation.

TRP channels play a significant role in mechanosensation.

One aspect of hair cell mechanosensation that remains unknown is the stiffness of the tip links.

For example, TRPA1 is thought to respond to noxious cold and mechanosensation.

Defective thermosensation or mechanosensation, often via ciliated epithelial cellular dysfunction.

A wide array of elements are involved in the process of mechanosensation, many of which are still not fully understood.

The bundle of cilia that projects from the surface of the hair cell is the organelle which participates in mechanosensation.

Defective thermosensation or mechanosensation.

While many details of mechanosensation remain to be discovered, the VS-3 system continues to offer important opportunities to advance our understanding of this crucial physiological process.

The cytoplasmic content of each of these differs significantly, leading researchers to doubt that the cytoplasm is the core of mechanosensation.

Key words: mechanosensation, noise analysis, sensory adaptation, encoding, dendritic conduction, efferent control, peripheral modulation.

For example, the blocking of certain subtypes results in a decrease in pain sensitivity, which suggest characteristics of that subtype with regard to mechanosensation.

The physiological foundation for the senses of touch, hearing and balance, and pain is the conversion of mechanical stimuli into neuronal signals: mechanosensation.

Epithelial Na+ channel (ENaC)/degenerin family members are involved in mechanosensation, blood pressure control, pain sensation, and the expression of fear.

TRPV4 plays a major role in mechanosensation, as well as osmosensory functions in nerve endings, endothoelia, and alveoli.

Mutations that affect the morphology of ciliated endings of these sensory neurons usually cause diverse phenotypes such as defective chemo- and mechanosensation.

Mechanosensation also contributes to cell growth and development through extracellular matrix (ECM) interaction and traction of integrin receptors which facilitate adhesion.