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However, he did forward answers to some e-mailed questions and sent documents defending malarial therapy.
Austrian physician Julius Wagner-Jauregg won the Nobel Prize for his invention of malarial therapy as a treatment for general paralysis of the insane (neurosyphilis).
Malarial therapy was followed in 1920 by barbiturate induced deep sleep therapy to treat dementia praecox, which was popularized by the Swiss psychiatrist Jakob Klaesi.
Among these we may note the Austrian psychiatrist Julius Wagner-Jauregg's malarial therapy for general paresis of the insane (or neurosyphilis) first used in 1917, and for which he won a Nobel Prize in 1927.
The Centers for Disease Control and Prevention opposes malarial therapy, and some medical experts have harshly criticized him for experimenting on humans in China when it was unthinkable that such a trial would have been approved in the United States.
The clinician-historian Joel Braslow argues that from malarial therapy onward to lobotomy, physical psychiatric therapies "spiral closer and closer to the interior of the brain" with this organ increasingly taking "center stage as a source of disease and site of cure."
Inspired by Julius Wagner-Jauregg's development of malarial therapy for the treatment of general paralysis of the insane, the French physician Maurice Ducosté reported in 1932 that he had injected 5 ml of malarial blood directly into the frontal lobes of over 100 paretic patients through holes drilled into the skull.