Mal de Meleda Keratosis Palmoplantaris Transgradiens of Siemens None Meleda disease is an extremely rare inherited skin disorder characterized by the slowly progressive development of dry, thick patches of skin on the palms of the hands and soles of the feet (palmoplantar hyperkeratosis).

Meleda disease is inherited as an autosomal recessive trait.

Mal de Meleda Keratosis Palmoplantaris Transgradiens of Siemens None Meleda disease is an extremely rare inherited skin disorder characterized by the slowly progressive development of dry, thick patches of skin on the palms of the hands and soles of the feet (palmoplantar hyperkeratosis).

Mal de Meleda Keratosis Palmoplantaris Transgradiens of Siemens None Meleda disease is an extremely rare inherited skin disorder characterized by the slowly progressive development of dry, thick patches of skin on the palms of the hands and soles of the feet (palmoplantar hyperkeratosis).