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The resulting products are lysolecithin and a fatty acid.
This enzyme is also called lysolecithin migratase.
In general, it acts on lysolecithin (which is formed by the action of PLA2 on lecithin).
Lysolecithin acyltransferase may refer to:
The widest variations were seen in chronic atrophic gastritis: a lysolecithin decrease and a phosphatidylcholine increase much greater than in duodenal ulcer.
The overall evaluation of phospholipid composition compared with healthy controls showed that the lysolecithin part becomes the lowest phospholipid componentin both peptic ulcer and atrophic gastritis.
Patients with duodenal ulcer showed a significant increase, in both absolute and percentage values, in phosphatidylcholine, phosphatidylethanolamine, and phosphatidylserine, and a decrease in phosphatidylinositol and lysolecithin compared with controls.
In the fungus Penicillium notatum, an enzyme called lysolecithin acylmutase has been reported that can catalyze this isomerization reaction at low pHs at which the uncatalyzed reaction occurs very slowly.
The group of chronic atrophic gastritis patients had a reduction in total phospholipids and in lysolecithin, phosphatidylethanolamine and phosphatidylinositol, and an absolute and percentage increase in phosphatidylcholine; variations in the other phospholipid classes were not significant.
In acute or chronic demyelinated lesions created in the rodent CNS by chemical agents such as lysolecithin or cuprizone, polydendrocytes proliferate in response to demyelination, and the proliferated cells differentiate into remyelinating oligodendrocytes.