lymphopenia

Consequences of lymphopenia may be infections and/or treatment related malignancies (see below).

Although a full blood count is never diagnostic, normocytic anemia and lymphopenia are common.

Side effects of ribavirin include hemolytic anemia and lymphopenia.

Flares also manifest with a relative lymphopenia.

Defective lymphocyte circulation can cause lymphopenia and impaired cell-mediated immunity.

Fludarabine is associated with profound lymphopenia, and as a consequence, increases the risk of opportunistic infections significantly.

It has been proposed as a measure to predict neutropenia, though some research indicates that it is less effective than lymphopenia.

Likewise, low lymphocyte levels are termed lymphopenia.

Lymphocytopenia, or lymphopenia, is the condition of having an abnormally low level of lymphocytes in the blood.

Polonium poisoning can cause nausea, vomiting, anorexia, and lymphopenia.

Additionally, the high but sub-lethal dose of radiation used leads to significant lymphopenia [ 37 ] .

Immune system problems: Decreased white blood cell counts including pancytopenia, leukopenia, lymphopenia, thrombocytopenia, agranulocytosis, and neutropenia.

Early reports indicated a tendency to relative neutrophilia and a relative lymphopenia - relative because the total number of white blood cells tends to be low.

Leukopenia (due to a reduced number of circulating lymphocytes or lymphopenia) occurs in as many as 40% of patients, but is rarely severe.

Most peculiarly, the extent of IL-2-induced thrombocytopenia and lymphopenia is associated with increased frequency of clinical responses [ 10].

The profound lymphopenia caused by fludarabine renders patients susceptible to transfusion-associated graft versus host disease, a fatal complication of blood transfusion.

Severe congenital neutropenia: due to GFI1 deficiency (with T/B lymphopenia)

Morbillivirus (measles virus) infection is known to cause lymphopenia, a reduction in the number of CD4+ T lymphocytes circulating in the blood.

Knockout mice which genetically lack IL-7 receptor exhibit thymic atrophy, arrest of T-cell development at the double positive stage, and severe lymphopenia.

Two genes have been identified - the MHC Class II gene and Gimap5, causing a severe T cell lymphopenia.

Montella L, Masci AM, Merkabaoui G, et al.: B-cell lymphopenia and hypogammaglobulinemia in thymoma patients.

After inoculation by the vector, the virus travels via lymphatics to lymph nodes, and replicates in macrophages and neutrophils, resulting in lymphopenia, leukopenia and fever.

In early 1975, Drs Arthur Ammann and Louis K. Diamond in San Francisco sent a specimen from a 5-year-old girl with lymphopenia and chronic infection.

Complications include postradioembolization syndrome (PRS), hepatic dysfunction, biliary complications, portal hypertension, radiation pneumonitis, gastrointestinal ulcers, vascular injury, and lymphopenia.

Most common adverse reactions (frequency 20%) in chronic and accelerated phase patients include thrombocytopenia, anemia, neutropenia, diarrhea, nausea, fatigue, asthenia, injection site reaction, pyrexia, infection, and lymphopenia.