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Antigen made from sterile pus aspirated from previously unruptured abscesses, produced a reaction in patients with lymphogranuloma inguinale when injected intradermally.
The Frei test was developed in 1925 by Wilhelm Siegmund Frei, a German dermatologist, to identify lymphogranuloma inguinale.
The Frei Test for Lymphogranuloma Inguinale: Experiences with Antigens Made from Mouse Brain.
'Lymphogranuloma venereum' ('LGV', also known as lymphopathia venerea, tropical bubo, climatic bubo, strumous bubo, poradenitis inguinales, Durand-Nicolas-Favre disease and lymphogranuloma inguinale) is a sexually transmitted disease caused by the invasive Biovar L1, L2, or L3 of 'Chlamydia trachomatis'.