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Palpable purpura and livedo reticularis can occur in some patients.
Livedo Reticularis may be present in all types.
Livedo refers to a form of skin discoloration.
A number of conditions may cause the appearance of livedo reticularis:
Purpura and livedo may be present.
It should not be confused with the more general term "cutis marmorata", which refers to livedo reticularis caused by cold.
Secondary livedo reticularis:
Neuropathia mucinosa cutanea is a cutaneous condition characterized by livedo reticularis on the legs and hyperesthesia.
It is also more strongly associated with miscarriage, and can cause a number of other symptoms (such as livedo reticularis of the skin and migraine).
Sneddon's syndrome manifests with elevated blood pressure (hypertension), a skin rash (livedo reticularis), and cerebrovascular disease.
Other common findings, although not part of the APS classification criteria, are thrombocytopenia, heart valve disease, and livedo reticularis.
Sneddon's syndrome may instead present with livedo racemosca, which involves larger, less organized patches of bluish-purple mottling of the skin.
Sneddon's syndrome (also known as "Idiopathic livedo reticularis with cerebrovascular accidents") is a form of arteriopathy characterized by several symptoms, including:
Generally, Livedo precedes cerebrovascular involvement by roughly ten years, and many years of cerebrovascular involvement precede the development of dementia, when it occurs.
More severe forms include livedo reticularis, which is a network (reticulum) of erythematous to purplish discoloration of the skin caused by the presence of an obliterative cutaneous capillaropathy.
Characteristics include multiple episodes of reduced blood flow to the brain (cerebral ischemia) and bluish net-like patterns of discoloration on the skin surrounding normal- appearing skin (livedo reticularis).
Idiopathic livedo reticularis - the most common form of livedo reticularis and is a completely benign condition of unknown cause affecting mostly young women during the winter.
Other than identifying and treating any underlying conditions in secondary livedo, idiopathic livedo reticularis itself may improve with warming the legs, but once established the skin discolouration may become permanent.
Livedo Reticularis and Cerebrovascular Accidents Sneddon's Syndrome None Sneddon syndrome is a rare progressive disorder affecting the blood vessels characterized by the association of a skin condition and neurological abnormalities.
CMTC is also used synonymously with congenital generalized phlebectasia, nevus vascularis reticularis, congenital phlebectasia, livedo telangiectatica, congenital livedo reticularis and Van Lohuizen syndrome.
Embolism to the legs causes a mottled appearance and purple discoloration of the toes, small infarcts and areas of gangrene due to tissue death that usually appear black, and areas of the skin that assume a marbled pattern known as livedo reticularis.