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It emerges first and forms from the outermost of the germ layers.

The proceeding graph represents the products produced by the three germ layers.

At some point after the different germ layers are defined, organogenesis begins.

Establishing three germ layers during gastrulation is another critical step in animal development.

Among animals, sponges show the simplest organization, having a single germ layer.

Because of its great importance, the neural crest is sometimes considered a fourth germ layer.

However, eventually gastrulation finishes and the three germ layers are complete.

It is followed by organogenesis, when individual organs develop within the newly formed germ layers.

We have included the germ layers in the primordium category.

The researchers found that there were tissues from all three germ layers growing in the recipient mouse.