lipophilicity

Increased lipophilicity of the carrier also results in a rate increase.

This difference is attributed to the greater lipophilicity of the former.

It is used to evaluate the lipophilicity of pharmaceutical products.

The group acted as a purification tool due to its high lipophilicity.

What they found was a little surprising; lipophilicity is not the leading characteristic for a drug to pass through the barrier.

For this reason, there must be a balance between lipophilicity and hydrophilicity of drug molecules.

He also discovered a relationship between the lipophilicity of general anaesthetics and their potency.

Because of their lipophilicity, organotins are regarded as membrane active.

This is because of the compounds increased lipophilicity.

The sulfonamide group was chosen to lower lipophilicity and increase solubility as seen in figure 7.

It is a highly cumulative poison, due to its high lipophilicity and extremely slow elimination.

The model used was based on lipophilicity and polarity indices of solutes.

The high lipophilicity and high polarity are properties key to this application.

Lipophilicity of the drug can affect cell membrane permeability.

When in plants, ethiofencarb is close to optimum lipophilicity as the plant breathes.

Meyer concluded that lipophilicity was the essential factor in the effectiveness of an anaesthetic.

For example ionization of any compound will increase the solubility in water, but decrease the lipophilicity.

Lake loading and/or lipophilicity could account for most of the variability of these substances in fish.

Increase in chlorination increases both stability and lipophilicity.

Because of its lipophilicity, benzene accumulates primarily in adipose tissue.

Three factors influence the distribution (movement) of molecules in the body solubility, lipophilicity and molecular size/shape.

It was suspected that propranolol's centrally induced side effects could be due to its high lipophilicity.

The lipophilicity index should be independent of the stationary phase and organic modifier concentration.

In addition, on account of its high lipophilicity, iofetamine rapidly penetrates the blood-brain-barrier.

Oral Isotretinoin is best absorbed when taken with a high-fat meal, because it has a high level of lipophilicity.