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A clear, quantitative connection between radiation and lethal mutations quickly emerged.
"That outrageously high rate of skin cancer and lethal mutations makes it a fascinating place."
These important mechanisms prevent potentially lethal mutations from being passed on to offspring.
Muller's work was increasingly focused on mutation rate and lethal mutations.
Numerous hypotheses have been advanced as to why such a lethal mutation has persisted and spread in the human population.
Do you have any idea of the incidence of lethal mutations on that planet?"
He hadn't succeeded in convincing anyone in the city of the lethal mutations even when they could observe all the facts.
If this shows a lethal mutation it is classified as a presumed mammalian mutagen.
People have identified five recessive lethal mutations in chickens that cause bilateral diplopodia.
The effects of zygotic lethal mutations on female germ-line functions in Drosophila.
Rabin winced at the thought of the resulting abnormally high rates of cancer and lethal mutations.
It was identified in 2001 during a screen for lethal mutations in yeast cells lacking a functional copy of the Sgs1 protein.
Lethal mutations are mutations that lead to the death of the organisms which carry the mutations.
The primary lesion leading to a dominant lethal mutation is a break in the chromosome, in this case, induced by radiation.
"It means that it produced an embryonic lethal mutation in males, Your Grace," Allison said simply.
A pupal lethal mutation with a paternally influenced maternal effect on embryonic development in Drosophila melanogaster.
Zosteriform speckled lentiginous nevus is a skin lesion that may be the result of a potentially lethal mutation.
He also described a lethal mutation in the mouse agouti locus at a time when such a mutation was unheard of.
A genetic screen for zygotic embryonic lethal mutations affecting cuticular morphology in the wasp Nasonia vitripennis.
For example, Clarence Little and William E. Castle did credit Cuénot with the discovery of the first lethal mutation.
At Columbia, Muller and his collaborator and longtime friend Edgar Altenburg continued the investigation of lethal mutations.
If instead only two of those mutants are viable, the rest being lethal mutations, then that sequence is poorly connected and most of its descendants will not reproduce.
Arguments wandered over a wide range of issues: salt levels, peroxide levels, radiation levels, the look of the land, possibly lethal mutations of genetically engineered microorganisms, and so on.
Lethal mutations at the chromosome-7 pink-eyed dilution (p)locus were recovered opposite the original p mutation, and are maintained by outcross to +/+ mice, with progeny testing for p.
Studies in Drosophila showed that recessive lethal mutations in multiple drosophila ORC subunits reduces the amount of BrdU (a marker of active replication), incorporated.