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Osmosis favors the movement of water into the lens fibers to reduce the high osmolarity.
This osmotic movement ultimately results in the swelling of lens fibers until they rupture.
The lens fibers form the bulk of the lens.
These tightly packed layers of lens fibers are referred to as laminae.
Mature lens fibers have no organelles or Cell nucleus.
It is caused by compression of older lens fibers in the nucleus by new fiber formation.
Blunt trauma causes swelling, thickening and whitening of the lens fibers.
The cells of the lens epithelium also serve as the progenitors for new lens fibers.
The lens is split into regions depending on the age of the lens fibers of a particular layer.
New lens fibers, generated from the lens epithelium, are added to the outer cortex.
The results of the current study support the hypothesis that alpha-crystallin plays an active role in the differentiation and growth of lens fiber cells.
The lens fibers that do not reach the poles form tight, interdigitating seams with neighboring fibers.
As mature lens fibers do not have mitochondria, approximately 80% of the glucose is metabolized via anaerobic metabolism.
The lens has three main parts: the lens capsule, the lens epithelium, and the lens fibers.
New lens fibers are generated from the equatorial cells of the lens epithelium, in a region referred to as the germinative zone.
Friedenwald was able to show that periphery lens fibers always dissolve before fibers at the equatorial region of the lens.
The lens fibers are linked together via gap junctions and interdigitations of the cells that resemble "ball and socket" forms.
The suture patterns become more complex as more layers of lens fibers are added to the outer portion of the lens.
This damaging cycle may play a pivotal role in accelerating the rupture of lens fibers during the most advanced, nuclear stage of the galactosemic cataract.
This is because osmotic swelling of lens fibers considerably strains LEC endoplasmic reticula.
Lens fiber membrane intrinsic protein is a protein that in humans is encoded by the LIM2 gene.
Lens fibers became liquefied after nine days of the diet, and nuclear cataract formation appeared after 15 days of the diet.
Injection of Noggin into lens fiber cells in mice significantly reduces the BMP4 proteins in the cells.
Galactitol, however, may accumulate in lens fibers, perturbing lens epithelial cell permeability and leading to cell death and cataract formation.
Metabolic changes of the crystalline lens fibers over time lead to the development of the cataract and loss of transparency, causing impairment or loss of vision.
MIP is the major component of lens fibre gap junctions.