leading strand

This 3' hydroxyl group is used as a primer for the leading strand synthesis.

This implies that these nicks must be present in the leading strand, and evidence for this has recently been found.

In most bacteria majority of the genes are encoded in the leading strand.

This means that nucleotide synthesis on the leading strand naturally occurs in the 5' to 3' direction.

For instance, the leading strand in Bacillus subtilis encodes 75% of the genes.

When this is complete, a single nick on the leading strand and several nicks on the lagging strand can be found.

This makes the speed of lagging strand synthesis much lower than that of the leading strand.

This molecular process prevents the leading strand from overtaking the lagging strand.

This primer serves to prime leading strand DNA synthesis.

Heading towards the replication fork, the leading strand is synthesized in a continuous fashion, only requiring one primer.

In addition, the highly transcribed genes, such as ribosomal proteins, have been described to located mostly on the leading strand in bacteria.

The leading strand is the template strand that is being replicated in the same direction as the movement of the replication fork.

On the leading strand, a polymerase "reads" the DNA and adds nucleotides to it continuously.

This polymerase synthesises leading strand DNA in eukaryotes.

The coding regions are mostly distributed on the leading strand; therefore, A over T richness is observed in Firmicute.

On the leading strand this route is continuous, but on the lagging strand it is discontinuous.

However, it has been reported that there is positive AT skew in the leading strand in some prokaryote, such as Firmicute.

Leading strand synthesis then proceeds continuously, while the DNA is concurrently unwound at the replication fork.

Occurs once at the origin on the leading strand and at the start of each Okazaki fragment on the lagging strand.

The leading strand receives one RNA primer while the lagging strand receives several.

This means that the piecewise generation of Okazaki fragments can keep up with the continuous synthesis of DNA on the leading strand.

Evangelicalism has therefore been described as "the third of the leading strands in American Protestantism, straddl[ing] the divide between fundamentalists and liberals".

The leading strand is the template strand of the DNA double helix so that the replication fork moves along it in the 3' to 5' direction.

Originally this asymmetric nucleotide composition was explained as different mechanism used in DNA replication between leading strand and lagging strand.

Primase also acts as a halting mechanism to prevent the leading strand from outpacing the lagging strand by halting the progression of the replication fork.