large granular lymphocyte

However, NK large granular lymphocyte leukemia (involving natural killer cells) is also possible.

Large granular lymphocytes include natural killer cells (NK cells).

Association of pure red cell aplasia with T large granular lymphocyte leukemia is well recognized, especially in China.

It is sometimes known as T-cell large granular lymphocyte leukemia (specifying involvement of the T cells).

T-cell large granular lymphocyte leukemia (T-LGL)

Sokol L, Loughran TP Jr: Large granular lymphocyte leukemia.

A null cell is a large granular lymphocyte without surface markers or membrane-associated proteins from B lymphocytes or T lymphocytes.

Bowman SJ, Sivakumaran M, Snowden N, et al.: The large granular lymphocyte syndrome with rheumatoid arthritis.

The leukemic cells have a diameter mildly greater than a large granular lymphocyte (LGL) and have azurophilic granules and nucleoli of varying prominence.

NK cells (also called LGL (large granular lymphocytes)) These kill with exactly the same methods as Tc, but have no interaction with any antigen.

Loughran TP Jr, Kidd PG, Starkebaum G: Treatment of large granular lymphocyte leukemia with oral low-dose methotrexate.

They do have numerous granules which provide their ability to kill cells and these granules are why NK cells have an alternate name, LGL, Large Granular Lymphocytes.

NK cells are defined as large granular lymphocytes (LGL) and constitute the third kind of cells differentiated from the common lymphoid progenitor generating B and T lymphocytes.

The demonstration that density gradient-isolated large granular lymphocytes were responsible for human NK activity, made by Timonen and Saksela in 1980, was the first time that NK cells had been visualized microscopically and was a major breakthrough in the field.

It is also known by the following terms: proliferation of large granular lymphocytes (LGLs), LGL leukemia, Tγ-lymphoproliferative disorder, and, in common with other T cell leukemias such as T-cell prolymphocytic leukemia, T-cell chronic lymphocytic leukemia.