lamina lucida

During suction blistering, the lamina lucida of the skin is cleaved from the underlying layers.

The lamina lucida appears as a low density clear zone medial to the epithelial basal cells.

This is transitional tissue composed of two zones, the lamina lucida and lamina densa.

Ideally, the basement membrane must contain a lamina lucida and a lamina densa.

Junctional epidermolysis bullosa is a skin condition characterized by blister formation within the lamina lucida of the basement membrane zone.

Anchoring filaments traverse the lamina lucida space and appear to insert into the electron dense zone, the lamina densa.

The lamina lucida is a component of the basement membrane which is found between the epithelium and underlying connective tissue (e.g.epidermis and dermis of the skin).

The structure of the epithelial basal lamina was also appeared close to normal: lamina densa and lamina lucida were well distinguishable with rare branching and duplication.

The electron-lucent zone is adjacent to the cells of the junctional epithelium and might be considered a continuation of the lamina lucida as both are seen to harbour hemidesmosomes.

The clear layer closer to the epithelium is called the lamina lucida, while the dense layer closer to the connective tissue is called the lamina densa.

Some theorize that the lamina lucida is an artifact created when preparing the tissue, and that the basement membrane is therefore equal to the lamina densa in vivo.