lactam

The lactam structure is the most common form of uracil.

In common with the other efforts the tail addition is based on the Ojima lactam.

Vince's work with this lactam eventually led to his synthesis of abacavir.

The lactam is formylated at position-5 and reduced to yield methyprylon.

This lactam lactim tautomerism can also be found in other molecules with a similar structure.

Talampicillin is a beta lactam antibiotic from the penicillin family.

The lactam is first treated with phosphoryl chloride to produce a dibenzothiazepine.

By cleaving the lactam ring, these antibiotics are rendered harmless to the bacteria.

This lactam is a versatile chemical intermediate used in organic and medicinal chemistry.

The molecule is a lactam, or cyclic amide.

Caprolactone is treated with ammonia at elevated temperatures to give the lactam:

Oxazolidinedione, which has two in-cycle keto groups (a carbamate and a lactam).

Macbecin has an unusual macrocyclic lactam structure.

This colourless solid is a lactam or a cyclic amide of caproic acid.

At optimum temperatures, a highly useful γ-lactam known as Vince Lactam is obtained.

It is formed when lactam undergoes tautomerization.

The resulting enol is converted to the lactam pyrithyldione by treating with ammonia and heating.

For example, cyclododecanone can be converted to the corresponding lactam, a monomer for the production of Nylon 12.

Protected secondary alcohol in Ojima lactam 7.1 during reaction with alcohol 7.2 in the tail addition.

Various strains tested have shown resistance to beta lactam antibiotics, lincosamides, macrolides, and quinolones.

Chlorosulfonyl isocyanate can be utilized as a dienophile to prepare Vince Lactam.

The Ojima lactam is an organic compound of some importance in the commercial production of Taxol.

This lactam was first synthesized by Iwao Ojima.

The final stage of the synthesis was the formation of the tail by addition of the Ojima lactam 42 to alcohol 41.

The lactam has found several applications in targeting an array of different diseased conditions by providing various non-nucleoside therapeutic molecules as well.