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There are two "professional" antigen-presenting cells: macrophages and dendritic cells.

Selection of the appropriate adjuvant, molecules that activate antigen-presenting cells to stimulate immune responses, is required.

They are often found within tissues where they can be activated by antigen-presenting cells upon infection.

An additional co-stimulatory signal is then produced by the antigen-presenting cell, leading to activation of the T cell.

There are three main types of professional antigen-presenting cell:

DCs are highly specialized and efficient antigen-presenting cells.

Cells called antigen-presenting cells bring foreign substances to the attention of specific T-cells and activate them.

They meet up with the antigen-presenting cells they were made to see, and suddenly the T-cell is tricked.

The drug disrupts the mating of the T cell and antigen-presenting cell.

These proteins occupy the cleft on antigen-presenting cells in such a way that T-cell activity is suppressed rather than activated.