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Spontaneous improvement occasionally happens and some juxta-articular lesions don't progress to collapse.
Osteonecrosis is believed to be a result of ischaemia of the juxta-articular bone for either a short or long time.
In juxta-articular lesions without symptoms, there is dead bone and marrow separated from living bone by a line of dense collagen.
The distribution of lesions differs with the type of exposure - the juxta-articular lesions being more common in caisson workers than in divers.
Weinberg et al. treated two patients with juxta-articular Dercum's disease with intralesional injections of methylprednisolone (Depo-Medrol).
The diagnosis is made by x-ray/MRI appearance and has five juxta-articular classifications and forehead, neck, and shaft classifications indicating early radiological signs.
Divers who have suffered from DON are at increased risk of future fracture of a juxta-articular lesion during a dive, and may face complications with future joint replacements.
In RA, there may be no changes in the early stages of the disease, or the x-ray may demonstrate juxta-articular osteopenia, soft tissue swelling and loss of joint space.