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Juvenile polyps are not associated with an increased incidence or risk of cancer.
This is mainly because of juvenile polyps developing adenomatous tissue.
Most juvenile polyps are benign, however, malignancy can occur.
Any number of juvenile polyps in a person with a family history of juvenile polyposis.
Juvenile polyps are hamartomatous polyps which often become evident before twenty years of age, but can also be seen in adults.
The free-swimming planula larvae eventually settle on the seabed and develop into juvenile polyps which found new colonies.
Juvenile polyposis syndrome is a syndrome characterized by the appearance of multiple juvenile polyps in the gastrointestinal tract.
People with juvenile polyps may require yearly upper and lower endoscopies with polyp excision and cytology.
Juvenile polyposis is defined by the presence of a specific type of hamartomatous polyp called a juvenile polyp, usually in the setting of a family history.
Germline mutations in SMAD4 predispose individuals to forming juvenile polyps and cancer,[61] and germline mutations have been found in 6 of 11 exons.
Hereditary mixed polyposis syndrome (HMPS) is a rare cancer family syndrome characterized by the development of a variety of colon polyp types, including serrated adenomas, atypical juvenile polyps, and adenomas, as well as colon adenocarcinoma.
The diagnosis of a juvenile polyp is based on its histologic appearance rather than age of onset, and the familial form is caused by mutations in the BMPR1A gene in 20% of cases and by mutations in the SMAD4 gene in another 20%.