junctional complex

A Plakin is a protein that associates with junctional complexes and the cytoskeleton.

The cells preserved their apical junctional complexes and well developed intercellular gap junctions.

These short actin filaments act as junctional complexes allowing the formation of the hexagonal mesh.

Recent data (2005) demonstrate that membrane associated actin is several fold less stable compared to components of the adherens junctional complex.

A type of junctional complex, they are localized spot-like adhesions randomly arranged on the lateral sides of plasma membranes.

This occurs at the same time as the loss of cytoskeletal adaptor proteins that are part of the junctional complex, including α/β-adducin and tropomyosin.

Paracellular transport can be enhanced through the displacement of zona occludens proteins from the junctional complex by the use of permeation enhancers.

JACOP is recruited to the junctional complex in epithelial cells and to cell-cell contacts in fibroblasts.

The authors suggested that the increased permeability may reflect alterations in the intercellular junctional complexes allowing enhanced entry into the intercellular and submucosal spaces.

Although the lateral is formed in the distal region of the cell it is not juxtaposed to the junctional complex or lateral cell periphery where Fz accumulates.

This brings the laterals close to the cell edges that are parallel to the proximal distal axis of the central core and the junctional complexes at these edges could provide orientation guidance.

They have features common to neoplastic cells of epithelial origins such as numerous microvilli, junctional complexes, abnormal nuclei and nucleoli, abnormal mitochondria, annulate lamellae, and lipoidal bodies.

Electron microscopic studies in 3 cases described intracytoplasmic mucin, convoluted oval nuclei, prominent nucleoli, homogeneous euchromatin with peripheral chromatin condensation, microvilli, junctional complexes, and primitive lumen formation.

The assembly of the hair at the cell periphery puts it in close proximity to the junctional complex perhaps allowing for direct interactions between the cortical and hair cytoskeletons [ 5 ] .

Thus, early in their development laterals are not close to the junctional complex or the prominent cortical cytoskeleton at the cell periphery and are unlikely to be getting any orientation guidance in this way.

Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels.

Terminal bar is a histological term given to the unresolved group of junctional complexes that attach adjacent epithelial cells on their lateral surfaces: the Zonula Occludens, Zonula Adherens, Macula Adherens and Macula Communicans.

Cells have developed several types of junctional complexes to serve these functions, and in each case, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighbouring cells as well as to proteins in the extracellular matrix .

The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic membrane occupation and recognition nexus (MORN) domain that shows specific affinity for the plasma membrane.