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Direct skin contact with Isocyanates can also cause marked inflammation.
The isocyanates may be isolated or trapped if they are the desired product.
However, it, like the other isocyanates, is an allergen and sensitizer.
The main ingredients to make a polyurethane are isocyanates and polyols.
In general, organic biurets are prepared by trimerization of isocyanates.
When exposed to moisture, isocyanates react with water and thus cure the adhesives.
Isocyanates used to make polyurethane must have two or more isocyanate groups on each molecule.
Most of the isocyanates are difunctional, that is they have exactly two isocyanate groups per molecule.
Today, most phosgene is used to produce isocyanates.
Overexposure to isocyanates can sensitize workers, making them subject to asthma attacks if they are exposed again.
It has a strong catalyst effect for the reactions of alicyclic and aliphatic isocyanates.
Characteristic of other isocyanates, it reacts with amines to give ureas.
HSE was not able to find any reference to the risk of occupational asthma from isocyanates.
Owing to the hazards associated with phosgene, the production of isocyanates requires special precautions.
The choice of linker between the two oxazolidine rings has a large impact on the performance when used to cure isocyanates.
Liquid resin blends and isocyanates may contain hazardous or regulated components.
Isocyanates should not be confused with cyanate esters and isocyanides, whose behaviors are very different.
Isocyanates react with water to form carbon dioxide:
Isocyanates also can react with themselves.
Both the isocyanates and polyols used to make polyurethanes contain on average two or more functional groups per molecule.
Polyurethanes, especially those made using aromatic isocyanates, contain chromophores which interact with light.
Chemical compounds that often trimerise are aliphatic isocyanates and cyanic acids.
Isocyanates are powerful irritants to the eyes and gastrointestinal as well as the respiratory tracts.
Ureas can also be formed from the reaction of isocyanates and water which forms a carbamic acid intermediate.
Persons developing sensitivity to isocyanates may have dangerous systemic reactions to extremely small exposures, including respiratory failure.