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It is involved in Ca(2+) ionophore control and host cell egress.
Due to this property, nonactin is also called "ammonium ionophore".
Influence of the ionophore, A23187, on the plastic behaviour of normal erythrocytes.
The ionophore is used in laboratories to increase intracellular Ca levels in intact cells.
Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus.
It is a nitrile, hydrazone and ionophore.
Calcium ionophore treatment is thought to mimic the natural signal responsible for the editing out of self-active T cells in the thymus.
The ionophore, however, stimulated dose dependent increases in [Ca 2 + ]i, steady state values being achieved within four to five minutes.
It has been used as an ionophore in ion selective electrodes, with good response to Pb and Ni.
Therefore, adeno-RGS3 infected pituitary cells were treated with a calcium ionophore (A23187).
Concentrations of PGE 2 were not measured in samples stimulated by calcium ionophore because limited material was available.
In contrast, only epithelial cells from ulcerative colitis showed an appreciable increase after calcium ionophore induction.
This drug is classified as an ionophore, which is an antibiotic that is naturally produced by a harmless bacteria strain.
Valinomycin (potassium ionophore I)
This ionophore is also used in experiments with membrane vesicles to create the electrochemical gradient, if such is required by the design of the experiment.
Nigericin acts as an H, K, Pb ionophore.
H + secretion can also be induced by exposure of resting parietal cells to the K + ionophore valinomycin.
Stimulation with calcium ionophore increased appreciably platelet activating factor activity in lamina propria cells from all groups.
The chemical acts essentially as an ionophore and reduces the ability of ATP synthase to function optimally.
His research on lasalocid, an ionophore antibiotic, as a control of feedlot bloat led to the commercial introduction of Bovatec.
Nonactin (ammonium ionophore I)
A protonophore, also known as a proton translocator, is an ionophore that allows protons to cross lipid bilayers.
It also acts as a divalent cation ionophore, allowing these ions to cross cell membranes, which are usually impermeable to them.
Glass (Hinke type) or resin-filled (Fluka ionophore 95291) pH-sensitive microelectrodes gave similar results.
An ionophore is a lipid-soluble molecule usually synthesized by microorganisms to transport ions across the lipid bilayer of the cell membrane.