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Interstitial implantation of radioisotopes is technically difficult in large tumors.
Interstitial implantation alone or with external-beam radiation therapy.
External-beam (i.e., photons or electrons) and/or interstitial implantation can be used.
Interstitial implantation combined with EBRT is being used in selected T3 patients, but little information is available.
External-beam radiation therapy (EBRT), interstitial implantation of radioisotopes, and radical prostatectomy are used.
External-beam radiation therapy augmented with interstitial implantation and multiple daily treatment schemes have given new insights into the use of radiation for this group of tumors.
Kuban DA, el-Mahdi AM, Schellhammer PF: I-125 interstitial implantation for prostate cancer.
Wazer DE, Kramer B, Schmid C, et al.: Factors determining outcome in patients treated with interstitial implantation as a radiation boost for breast conservation therapy.
Radical prostatectomy, external-beam radiation therapy (EBRT), and interstitial implantation of radioisotopes are each employed in the treatment of stage II prostate cancer with apparently similar therapeutic effects.
Radiation therapy for lip and oral cavity cancers can be administered by external-beam radiation therapy (EBRT) or interstitial implantation alone, but for many sites the use of both modalities produces better control and functional results.
Interstitial implantation of radioisotopes (i.e., iodine I 125, palladium, and iridium) done through a transperineal technique with either ultrasound or computed tomography (CT) guidance is being done in carefully selected patients with T1 or T2a tumors.