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Under the microscope distributing arteries can be identified by their clearly defined internal elastic lamina.
In fungal rhinosinusitis, the organism has predilection for internal elastic lamina during phase of spread.
It is made up of one layer of endothelial cells and is supported by an internal elastic lamina.
Reduplication of internal elastic lamina can be seen in elderly individuals due to intimal fibroplasia, which is part of aging process.
There is small amount of subendothelial connective tissue between basement membrane of endothelial cells and internal elastic lamina.
Endothelial cells made close association with smooth muscle in regions of the inner aspect of the artery that was free of internal elastic lamina (Fig.
It stains muscle tissue in yellow, connective tissue in red and elastic structures (like internal elastic lamina) in black color.
In chronic allograft nephropathy, disruption or reduplication of internal elastic lamina can be observed, which causes narrowing of the lumen and downstream ischemia.
The larger blood vessels (interlobar and arcuate arteries) show reduplication of internal elastic lamina along with fibrous thickening of the media (fibroelastic hyperplasia) and the subintima.
The internal elastic lamina or internal elastic lamella is a layer of elastic tissue that forms the outermost part of the tunica intima of blood vessels.
It is characterized by generalised calcification of the arterial internal elastic lamina, leading to rupture of the lamina and occlusive changes in the tunica intima with stenosis and decreased elasticity of the vessel wall.
However studies in animals suggest that a predominantly medial pattern of vascular calcification reflects different underlying mechanisms of disease, and despite involvement of the internal elastic lamina, evidence of inflammation is rare in Monckeberg's arteriosclerosis.
In elastic arteries such as the aorta, which have very regular elastic laminae between layers of smooth muscle cells in their tunica media, the internal elastic lamina is approximately the same thickness as the other elastic laminae that are normally present.
Additionally, IVUS examinations, as they were done more frequently, served to reveal and confirm the autopsy research findings of the late 1980s, showing that atheromatous plaque tends to cause expansion of the internal elastic lamina, causing the degree of plaque burden to be greatly underestimated by angiography.
Tunica intima (the thinnest layer): a single layer of simple squamous endothelial cells glued by a polysaccharide intercellular matrix, surrounded by a thin layer of subendothelial connective tissue interlaced with a number of circularly arranged elastic bands called the internal elastic lamina.