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Various insertional mutagenesis techniques may also be used to study the function of particular gene.
The term jumper's knee was first used in 1973 to describe an insertional tendinopathy.
The insertional activity provides valuable information about the state of the muscle and its innervating nerve.
Jerry Rosario has done a decade of insertional services among the dalits and the poor.
She was able to go off the medicine but says she was left with "very severe insertional pain."
Through these collections, insertional mutants are available for most genes in arabidopsis.
In the examined muscles, no abnormal insertional activity or fibrillation potentials were noted.
Not all integrating viruses cause insertional mutagenesis, however.
An alternative strategy for insertional mutagenesis has been used in vertebrate animals to find genes that cause cancer.
About ten years ago, Hopkins started to develop insertional mutagenesis in zebrafish (Figure 2).
There is concern that insertional mutagenesis due to integration into the host genome might lead to cancer or leukemia.
In some cases, the adverse effects result from disruption of essential genes within the patient's genome by insertional inactivation.
Virus insertional mutagenesis is only possible with a replication competent virus.
This process is referred to as insertional mutagenesis or transposon mutagenesis.
Background Gene entrapment has provided effective strategies for insertional mutagenesis of mammalian cells in culture.
In 1994, a new allele of reeler was obtained by means of insertional mutagenesis.
Insertional mutagenesis (but not lethal for the plant cell - as the organism is diploid)
This is advantageous as insertional mutagenesis is avoided.
Insertional mutagenesis is when transposons function as vectors to help remove and integrate genetic sequences.
Initially, this was done by generating random mutations in an organism, often with radiation or insertional mutagenesis (ex.
The SB transposon is a powerful tool for insertional mutagenesis in many vertebrate species.
With this approach there is increased risk of insertional mutagenesis; however, the risk can be reduced by using an integrase-deficient lentivirus.
Currently transposons can be used in genetic research and recombinant genetic engineering for insertional mutagenesis.
Insertional inactivation focuses on suppressing the expression of a gene by disrupting its sequence with an insertion.
Avian leukosis virus is an example of a virus that causes a disease by insertional mutagenesis.