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It has the benefit of having no negative inotropic properties.
Class I agents have the most potent negative inotropic effect and may cause heart failure.
For some studies the concentration of calcium was varied to produce an inotropic effect.
This results in slower inactivation, which has a positive inotropic effect on the heart.
Inotropic therapy may also speed up the heart's rhythm.
For severe heart failure, therapy with inotropic drugs may work when other medicines fail.
Isoprenaline has positive inotropic and chronotropic effects on the heart.
This may contribute to its positive inotropic effect on cardiac myocytes.
This is known as the negative inotropic effect of calcium channel blockers.
She required continuous inotropic support and was now developing interstitial emphysema.
The increased intracellular calcium gives a positive inotropic effect.
Contractility may be iatrogenically altered by the administration of inotropic agents.
It is a calcium sensitizer with positive inotropic and vasodilator effects.
Medications that make the heart muscle pump harder (inotropic agents)
Positively inotropic agents increase the strength of muscular contraction.
Current inotropic drug therapies such as dobutamine, are palliative and not a cure.
Negatively inotropic agents weaken the force of muscular contractions.
Agents that are dromotropic are often (but not always) inotropic and chronotropic.
It is considered an inotropic agent.
The initial increase in circulating norepinephrineis thought to maintain cardiac function through inotropic mechanisms.
Resuscitation restored the circulation, but the patient required artificial ventilation and inotropic support thereafter.
For example, parasympathetic stimulation is usually negatively dromotropic, inotropic, and chronotropic.
Anthopleurins slow down inactivation of the sodium channels As a result, they can have positive inotropic effects on the whole heart.
Levosimendan is indicated for inotropic support in acutely-decompensated severe congestive heart failure.
Dihydropyridine calcium channel blockers can produce negative inotropic effects and exacerbate heart failure.