induced fit model

This led him to propose the induced fit model for enzyme catalysis.

The favoured model for the enzyme-substrate interaction is the induced fit model.

Describe the induced fit model.

There are two proposed models of how enzymes fit to their specific substrate: the lock and key model and the induced fit model.

Walker motif A-binding has been shown to cause structural changes in the bound nucleotide, along the line of the induced fit model of enzyme binding.

AgTx2 has been found to undergo conformational changes when bound to the 'Shaker K' channel which suggests the induced fit model may be present in toxin-channel interaction.

The induced fit model is a development of the lock-and-key model and assumes that an active site is flexible and it changes shape until the substrate is completely bound.

These complexes are a subset of macrocyclic molecular receptors and their structure is that the two "arms" that bind the guest molecule between them are only connected at one end leading to a certain flexibility of these receptor molecules (induced fit model).