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The inbreeding coefficient quantifies the increase in homozygosity which results.
Together, they are called F-statistics, and are derived from F, the inbreeding coefficient.
This percentage is called "inbreeding coefficient".
Wright was the inventor/discoverer of the inbreeding coefficient and F-statistics, standard tools in population genetics.
The overall rise in homozygosity is quantified by the inbreeding coefficient (f or φ).
The definition of the inbreeding coefficient now most widely used is mathematically equivalent to that of Wright."
The inbreeding coefficient is unstable as the expected value approaches zero, and thus not useful for rare and very common alleles.
He is the discoverer of the inbreeding coefficient and of methods of computing it in pedigrees.
Consider a non-sexual population of fixed size , and call the inbreeding coefficient of generation .
Typical inbreeding coefficient percentages are as follows, assuming no previous inbreeding between any parents:
This computation trivially extends to the inbreeding coefficients of alleles in a sexual population by changing to (the number a gametes).
The lions kept in the framework of the Species Survival Plan consisted of animals with high inbreeding coefficients.
Finland's breeding program has used breeding consultants and computer programs to determine inbreeding coefficients to keep the risk of genetic diseases low given the small population.
The inbreeding coefficient, F (see also F-statistics), is one minus the observed frequency of heterozygotes over that expected from Hardy-Weinberg equilibrium.
RIX progeny made among members of a single diallele RI set will be similar to an F2 intercross with an inbreeding coefficient of 0.5.
Crosses between members of completely different RI sets (for example, AXB1 crossed to LXS80) will have an inbreeding coefficient close to zero.
"Dr. Wright introduced the inbreeding coefficient "F" as the correlation between uniting gametes in 1922, and most of the subsequent theory of inbreeding has been developed from his work.
The average inbreeding coefficient per colony is higher in Acromyrmex striatus than in Acromyrmex heyeri, which may reflect the different patterns of production of sexual individuals and nuptial flight of those two species.
The two population genetic quantities identified by Wright were the one-generation increase in variance across replicate populations (variance effective population size) and the one-generation change in the inbreeding coefficient (inbreeding effective population size).
A genetic study has been done in Germany using the Elo, calculating the proportion of genes of the different founder breeds, of the inbreeding coefficient and relationship coefficients, and the percentage of stillborn puppies in litters.
The Jack Russell Terrier Club of America code of ethics specifies that "a terrier will be rejected for registration if the inbreeding coefficient is more than 16 percent" in an effort to lessen hereditary disease in the breed.
Databases are maintained by the Nederlandse Vereniging voor Stabij- en Wetterhounen (Club for the Stabij and Wetterhoun) and De Wetterhoun Vereniging Nederland for understanding pedigrees and computing inbreeding coefficients.
In maintaining captive breeding groups the aim must be to retain, if possible, the inbreeding coefficient of wild groups, and this is hampered not only by the limited captive stock available among the world's zoos but also our ignorance of the coefficient in the wild.
Alternatively, the effective population size may be defined by noting how the average inbreeding coefficient changes from one generation to the next, and then defining N as the size of the idealized population that has the same change in average inbreeding coefficient as the population under consideration.