immunoglobulin class switching

B cells of the immune system perform genetic recombination, called immunoglobulin class switching.

Immunoglobulin class switching can be used to change the class of the heavy chain, but not of the light chain.

This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.

MULTISTRANDED DNA structures based upon guanine association have been proposed to be important in the structure of chromosome telomeres and in immunoglobulin class switching.

He was the first to describe the role of T cells in immunoglobulin class switching and to identify a novel T-cell-derived cytokine (446-BCDF) that stimulates antibody secretion by human B cells.

Immunoglobulin class switching (or isotype switching or isotypic commutation or class switch recombination(CSR)) is a biological mechanism that changes a B cell's production of antibody from one class to another, for example, from an isotype called IgM to an isotype called IgG.