immune-mediated disease

Immune-mediated diseases are conditions which result from abnormal activity of the body's immune system.

It is thought to be an immune-mediated disease.

However, when myasthenia gravis occurs in older dogs it is thought of as an immune-mediated disease.

This discovery has opened the way to novel studies on the role of the gut microbiome in regulating immune-mediated diseases.

Autoimmune diseases are a subset of immune-mediated diseases.

VKH syndrome is an immune-mediated disease.

Other diseases affecting dogs include endocrine diseases, immune-mediated diseases, and reproductive diseases.

This allele is also associated with hypothyroidism which implies that this allele increases susceptibility for endocrinopathic immune-mediated diseases.

Immunosuppressive therapy for RA often improves granulocytopenia and splenomegaly; this finding reflects the fact that Felty's syndrome is an immune-mediated disease.

MHC genes represent candidate susceptibility in canines; some alleles promote protection against immune-mediated diseases and some increase susceptibility.

Like other immune-mediated diseases, most animals receive an initial course to stop the inflammation and treatment is tapered off to the lowest dose that keeps the disease in remission.

Dogs have been selectively bred for different genotypes and phenotypes, selection in the DLA genome can lead to an increase in the prevalence of immune-mediated diseases.

Viruses have long been suspected as triggers for immune-mediated diseases such as multiple sclerosis but showing a direct role for viral causation is difficult in those diseases, and mechanisms whereby viral infections could lead to autism are speculative.

In August 2004, Professor Menter founded the International Psoriasis Council (IPC), an international organization dedicated to raising international consciousness and understanding of psoriasis as a serious immune-mediated disease with major quality of life implications.

Orbital pseudotumor has also been observed in association with Crohn's disease, systemic lupus erythematosus, rheumatoid arthritis, diabetes mellitus, myasthenia gravis, and ankylosing spondylitis all of which strengthen the basis of IOI being an immune-mediated disease.

NIAID conducts and supports research - at NIH, throughout the United States, and worldwide to study the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses.

The NIMML brings together immunologists, computer scientists, mathematicians, biochemists and engineers studying the basic mechanisms of disease processes, but also exploiting new knowledge related to improved understanding of biological systems to more directly bring about cures for important infectious and immune-mediated diseases.

The Nutritional Immunology and Molecular Medicine Laboratory (NIMML) is a research organization founded in 2002 with the mission of understanding fundamental mechanisms of gut enteric immunity and identifying biomarkers and therapeutic targets for inflammatory and immune-mediated diseases.

Apart from these external effects on the organism, there are also defence reactions regarding the body's own cells, e.g. in the scope of the bodily reactions on cancer and the lacking reaction of a body on healthy cells in the scope of an immune-mediated disease.

Autoimmune diseases, the outbreak and/or course of which can be visible in the individual genome of the organism, include multiple sclerosis, diabetes type I, rheumatoid arthritis and Crohn's disease (an example for an immune-mediated disease without genetic disposition is HIV, which is caused by virus).

However, the concept of vaccine overload is biologically implausible, vaccinated and unvaccinated children have the same immune response to non-vaccine related infections, and autism is not an immune-mediated disease, so claims that vaccines could cause it by overloading the immune system goes against current knowledge of the pathogenesis of autism.