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The gigantocellular nucleus excites the hypoglossal nucleus, and can play a role in the actions of the said nerve.
The hypoglossal nucleus, which contains general somatic efferent fibers (GSE).
This nucleus has been known to innervate the caudal hypoglossal nucleus, and responds to glutamateric stimuli.
A blockage (such as in a stroke) will injure the pyramidal tract, medial lemniscus, and the hypoglossal nucleus.
Their axons project down to the bulbar/spinal motor systems, such as the hypoglossal nucleus which harbors the motor neurons of the tongue muscles.
Also, it projects to the facial nucleus, hypoglossal nucleus and parabrachial area along with parts of the caudal parvocellular reticular formation.
The nerve arises from the hypoglossal nucleus and emerges from the medulla oblongata in the preolivary sulcus separating the olive and the pyramid.
The hypoglossal nucleus is a cranial nerve nucleus, and it extends the length of the medulla, and being a motor nucleus, is close to the midline.
In focus was the discovery of prey-selective neurons in the optic tectum, whose axons could be traced towards the snapping pattern generating cells in the hypoglossal nucleus.
By contrast, the hypoglossal nucleus, which contains α-MNs that innervate the tongue, is found in the medulla, the most caudal (i.e., towards the bottom) of the brainstem structures.
The hypoglossal nucleus receives rhythmic excitatory inputs also from brainstem respiratory neurons within the pre-Boetzinger complex, which appears to play an important role in the origin of respiration rhythmogenesis.
In the upper part of the medulla oblongata, the hypoglossal nucleus approaches the rhomboid fossa, where it lies close to the middle line, under an eminence named the hypoglossal trigone.
Friedland, D.R., A.R. Eden and J.T. Laitman (1995) Naturally occurring motoneuron cell death in rat upper respiratory tract motor nuclei: A histological, fast-DiI and immunocytochemical study in the hypoglossal nucleus.
Rhythmic movements of the tongue, that participate in swallowing, mastication and respiration, are driven by hypoglossal nuclei, which receive inputs from the dorsal medullary reticular column (DMRC) and the nucleus of the tractus solitarius (NTS).