hyperosmolality

Only a weak antiseptic effect, due to hyperosmolality of the solution above 0.9%.

They are also susceptible to hyperosmolality from medium evaporation.

Decreased CSF pressure can indicate complete subarachnoid blockage, leakage of spinal fluid, severe dehydration, hyperosmolality, or circulatory collapse.

Wolf P, Simon M. Dimethyl sulphoxide (DMSO) induced serum hyperosmolality.

Responses may include "hypotension, bradycardia... QRS and T abnormalities on the ECG, arrhythmia, cardiac arrest, serum hyperosmolality, lactic acidosis, and haemolysis".