hydroxamic acids

Hydroxamic acids are commonly synthesized from their corresponding esters.

Hydroxamic acids can be synthesized from aldehydes via the Angeli-Rimini reaction.

Bilger's studies of nitrogenous compounds began with her thesis work, which concerned hydroxylamines and hydroxamic acids.

Esters can be converted to isocyanates through intermediate hydroxamic acids in the Lossen rearrangement.

Hydroxamic acids, such as salicylhydroxamic acid, and oximes are commonly utilized in metallacrown ligands.

Hydroxamic acids:

Many hydroxamic acids, such as salicylhydroxamic acid, are utilized as ligands in the synthesis of metallacrowns.

Some hydroxamic acids (e.g. vorinostat, belinostat, panobinostat, and trichostatin A) are HDAC inhibitors with anti-cancer properties.

Urbanski T, Hornung S, Slopek S, Venulet J. 1952 New hydroxamic acids as antitubercular agents.

Hydroxylammonium chloride is used in organic synthesis for preparation of oximes and hydroxamic acids from carboxylic acids, N- and O- substituted hydroxyamines, and addition reactions of carbon-carbon double bond.

DIMBOA is a member of a group of hydroxamic acids (also known as benzoxazinoids) that serve as a natural defense against a wide range of pests, including insects, pathogenic fungi and bacteria.

Hydroxylammonium sulfate is used in organic synthesis to convert aldehydes and ketones to oximes, carboxylic acids and their derivatives (e.g. esters) to hydroxamic acids, isocyanates to N-hydroxyureas and nitriles to amidoximes.

He devoted his attention chiefly to organic chemistry and published papers on nitro-paraffin salts, alkyl derivatives of hydroxylamine, preparation of hydroxamic acids from hydroxylamines, electron conception of valence, and preparation of electromeres.