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Arterioles and small arteries show profound changes, with hyalinization of the entire wall thickness.
Histological examination of tissue attained by fine needle aspiration cytology may demonstrate dilated ducts with periductal fibrosis, increased subareolar fat, and hyalinization of the stroma.
(Several have) gynecomastia..." He also described that a testicular biopsy shows "the atrophy and hyalinization of the seminiferous tubules with preservation of the Leydig or interstitial cells."
Consequent ischemia will produce tubular atrophy, interstitial fibrosis, glomerular alterations (smaller glomeruli with different degrees of hyalinization - from mild to sclerosis of glomeruli) and periglomerular fibrosis.
Characteristic lung tissue pathology in nodular silicosis consists of fibrotic nodules with concentric "onion-skinned" arrangement of collagen fibers, central hyalinization, and a cellular peripheral zone, with lightly birefringent particles seen under polarized light.
According to the characteristics of the defect or abnormality, the sclerotic lesion was excised and liquefied fat was aspirated; the excised samples indicated biological changes in the intramammary fat grafts - fat necrosis, calcification, hyalinization, and fibroplasia.