histocompatibility antigen

Other studies have failed to show any relationship between these histocompatibility antigens and susceptibility.

In fact, many transplants have been successful when matched for only five of the six major histocompatibility antigens.

Immunologists had discovered the major histocompatibility antigens in their studies of transplanted organs.

Two major types of isoantigens are blood group antigens and histocompatibility antigens.

Major histocompatibility antigen testing may be performed to investigate genetic susceptibility to uveitis.

Minor histocompatibility antigens are due to normal proteins that are in themselves polymorphic in a given population.

Gorer is credited with the co-discovery of histocompatibility antigens and the elucidation of their genetic regulation.

The minor histocompatibility antigen 13 is a nonamer peptide that originates from a protein encoded by the H13 gene.

If a related polymorphism exists, and if the HM13 serves as a Minor histocompatibility antigen, however, remains to be addressed.

Kidd antibodies are capable of behaving as histocompatibility antigens in renal transplants and may be responsible for allograft rejection in some cases.

There is an association with the HLA-B27 histocompatibility antigen, which is present in 65% of patients with erythema nodosum.

A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient.

His professional scientific career has revolved around transplantation and transplantation biology, with a major interest in the immune response to histocompatibility antigens and its suppression.

Els Goulmy (born 27 November 1946, The Hague) is professor of transplantation biology, especially regarding minor histocompatibility antigen, at Leiden University.

Minor histocompatibility antigen (a.k.a. MiHA) are receptors on the cell surface of donated organs that are known to give an immunological response in some organ transplants.

In a fully H-2 incompatible chimera, T cells of donor origin can respond to minor histocompatibility antigens in association with either donor or host H-2 type.

HLA class I histocompatibility antigen, alpha chain F is a protein that in humans is encoded by the HLA-F gene.

In Britain, researchers are studying a new method of matching bone marrow donors and recipients by typing the DNA (the material that makes up genes) that specifies certain histocompatibility antigens.

Another research project funded by the CLIC Trust, the 'Histocompatibility Antigens Project', looked at the antigens on the surface of cells forming the tumours of childhood.

For this purpose T2 transfectants were tested with an HLA-A2.1-restricted cytotoxic T lymphocyte (CTL) clone recognizing a minor histocompatibility antigen (HA-2).

She stayed on in Wiley's lab in a postdoctoral position where she ultimately solved the first crystal structure of an MHC protein - the HLA-A2 human histocompatibility antigen.

The histocompatibility antigen B27 (B27) was determined by Terasaki's joint-to-thyroid function test (Cis bio international Groupe ORIS Cedex-France) using radioimmunoassay.

In 1982, he took up a position as Clinical Fellow in Immunology with Hugh McDevitt at Stanford University, California, USA, where he worked on histocompatibility antigens and autoimmune disease.

A hint that certain genetic factors known as HLA (for histocompatibility antigens) play a role in progression of H.I.V. has come from studies led by Dr. Robert Winchester's team at Columbia University's College of Physicians and Surgeons.

HLA class II histocompatibility antigen gamma chain also known as HLA-DR antigens-associated invariant chain or CD74 (Cluster of Differentiation 74), is a protein that in humans is encoded by the CD74 gene.