high throughput screening

It is typically used as a secondary screening technique in high throughput screening.

High throughput screening assay has also shown good efficiency in some in vivo models.

Located in Eastern Europe, it is a provider of high throughput screening compounds, chemical building blocks and fine chemicals.

P. fluorescens is a metabolically versatile organism, allowing for high throughput screening and rapid development of complex proteins.

To overcome this challenge, mutagenesis and high throughput screening methods have been used to create meganuclease variants that recognize unique sequences.

For this reason high throughput screening (HTS) of small molecular libraries could be the answer to finding a better remedy.

In collaboration with pharmaceutical companies UbiQ develops and manufactures high throughput screening assay reagents.

Due to sensor configuration, the technique is highly amenable to both purified and crude samples as well as high throughput screening experiments.

This property permits evaluation of intracellular protein interactions for use in high throughput screening of drug candidates for their effect on specific cellular pathways.

Automation: high throughput screening, LIMS, robotics.

Classical High throughput screening robotics are now being tied closer to cell biology, principally using technologies such as High-content screening.

When such high throughput screening is applied in nutrition research, it allows the examination of how nutrients affect the thousands of genes present in the human genome.

The high throughput Screening facility is now upgraded to High content facility to undertake mechanism of action molecules under discovery pipeline and hit to lead conversion.

It covers scientific and technical applications and advances in areas such as lab automation and robotics, virtual screening, and high throughput screening.

High throughput screening (HTS) usually gives low hit rates in identifying the inhibitors but virtual screening (VS) can give higher rates.

Other methods, such as virtual high throughput screening, where screening is done using computer-generated models and attempting to "dock" virtual libraries to a target, are also often used.

Solicitation of Assays for High Throughput Screening (HTS) to Discover Chemical Probes (R21)

A High Throughput Screening (HTS) facility is a central component of the Center for Chemical Genomics (CCG).

IdMOC can also be used for routine and high throughput screening of drugs with desirable ADME or ADME-Tox properties.

This is especially the case in the context of life sciences, where the availability of high throughput screening techniques for the different omics fields and the perceived complexity, makes the science predominantly data driven.

Use of automation technologies normally employed in the automative industry for ultra high throughput screening (uHTPS) enabling cost effective screening of up to 2 million compounds per day.

Current medicinal chemistry activities are focusing on the combined use of high throughput screening and structure-based design, coupled to the evaluation of the compounds in robust and mechanistically- informative biological assays.

The institute has made an endeavour in this direction by setting up in-house facilities for both Combinatorial chemistry and High throughput screening (HTS) as tools in the Institute's drug discovery programme.

Solicitation of Compounds for High Throughput Screening (HTS) in the Molecular Libraries Screening Centers Network (MLSCN)

Protein design labs and Signature BioScience Signature BioSciences acquired Protein Design Lab's Small Molecule Group access its high throughput screening and small molecule drug discovery efforts.