hereditary nephritis

Alternatively, it may also be known as X-linked hereditary nephritis.

Alport syndrome or hereditary nephritis is a genetic disorder characterized by glomerulonephritis, endstage kidney disease, and hearing loss.

MHA is also a feature of the Alport syndrome (hereditary nephritis with sensorineural hearing loss).

Also, there are no systemic manifestations, so presence of hearing impairment or visual impairment should prompt a search for hereditary nephritis such as Alport syndrome.

The disease has been shown to be a model for hereditary nephritis (HN) in humans in that the disease resembles that of the human disease.

Epstein and co-workers described four patients from two kindred's who had hereditary nephritis and nerve deafness indistinguishable from Alport's syndrome in association with macrothrombopathic thrombocytopenia.

Polycystic kidney disease (PKD) and Bull Terrier hereditary nephritis (BTHN) are autosomal dominant diseases.

Also known as Hereditary nephritis, it is caused by a nonsense mutation in codon 1027 of the COL4A5 gene on the X chromosome (glycine to stop codon), which is similar to Alport's syndrome in humans.