hepatoblastoma

One study suggests that low birth weight might be a risk factor for hepatoblastoma.

Hepatoblastoma is a rare form of Liver cancer occurring most frequently in children.

Approximately 10% to 20% of children with hepatoblastoma are stage IV.

The most common method of testing for hepatoblastoma is to a blood test checking the Alpha-fetoprotein.

Hepatoblastoma: A type of liver cancer that usually does not spread outside the liver.

Both Wilms tumor and hepatoblastoma can usually be cured if diagnosed early.

The most common types of tumors developed in patients are the Wilms tumor and hepatoblastoma.

Chemotherapy can often decrease the size and extent of hepatoblastoma, allowing complete resection.

The overall 3- to 5-year survival for children with stage III hepatoblastoma is less than 70%.

Complete removal is possible more often for hepatoblastoma than for hepatocellular carcinoma.

Accumulating evidence suggests that hepatoblastoma is derived from a pluripotent stem cell.

Treatment of stages I and II hepatoblastoma may include the following:

Hepatoblastoma occurs most often in children.

Surgical resection of distant disease has also contributed to the cure of children with hepatoblastoma.

Risk factors for hepatoblastoma include the following:

Survival trends in children with hepatoblastoma.

Cure of hepatoblastoma or hepatocellular carcinoma requires gross tumor resection.

The overall 3- to 5-year survival for children with stage IV hepatoblastoma vary widely based on published reports, from 20% to approximately 60%.

The outcome for metastatic hepatoblastoma at diagnosis is poor, but long-term survival and cure is possible.

Multiple cases of hepatoblastoma have been described in children with an APC mutation.

Trisomy 18, as well as other trisomies (associated with hepatoblastoma)

In very rare instances, association with other tumors, such as nevus sebaceus and hepatoblastoma are documented.

Either mechanism can be associated with an increased incidence of embryonal tumors including Wilms tumor and hepatoblastoma.

Hepatoblastoma arises from precursors of hepatocytes and can have several morphologies, including the following:

Low birth weight (associated with hepatoblastoma)