hepatic failure
hepatic insufficiency
hepatocellular insufficiency

Mortality in patients with fulminant hepatic failure is over 40%.

Unfortunately, a small number of patients develop Fulminant hepatic failure, which is very serious.

Exercise extreme caution in babies with renal or hepatic failure.

The association with pancreatitis has been reported but prognosis usually depends on the hepatic failure.

Fulminant hepatic failure associated with the use of black cohosh: a case report.

There is no significant change in pharmacokinetics in subjects with hepatic failure.

I counted the days to bye-bye, liver, hello, hepatic failure.

To be sure, they'd promised me three weeks before acute hepatic failure, but that hadn't been meant to include this sort of bone-breaking work.

It seems clear that only hepatic transplantation will save such patients with severe hepatic failure.

Three patients underwent successful liver transplantation and two others died of hepatic failure while awaiting transplant surgery.

Fatal fulminant hepatic failure induced by a natural therapy containing kava.

This usually leads to failure to thrive, hepatic failure, and the need for liver transplantation.

A few people may have more severe liver disease (fulminant hepatic failure), and may die as a result.

Until now there have been few reports on hepatic failure caused by disorders of mitochondrial oxidative phosphorylation.

Severe hepatic failure related to nevirapine treatment.

High prevalence of potentially hepatotoxic herbal supplement use in patients with fulminant hepatic failure.

Fulminant hepatic failure from drug-induced hepatotoxicity may require liver transplantation.

Fulminant hepatic failure has a very high mortality, especially when caused by acute viral hepatitis, which is the most common cause of this syndrome.

Duloxetine has also been associated with cases of hepatic failure and should not be prescribed to patients with chronic alcohol use or liver disease.

As previously mentioned, there is a report of successful liver transplantation in a 36 year old man with acute hepatic failure related to piroxicam usage.

Specifically, endogenous benzodiazepine-like substances may play a role in delirium associated with hepatic failure [ 1].

However, rare cases of fulminant hepatic failure have occurred during childhood HBV infection (647).

Hepatotoxicity (including hepatic failure)

It is not recommended for use in hepatic failure since it can precipitate hepatic encephalopathy.

This may cause fatty liver, hepatitis, fibrosis and sclerosis leading to cirrhosis and finally hepatic failure.

For patients with renal or hepatic insufficiency, patient can take 1 tablet by mouth once a day.

Requires dose adjustment in moderate to severe hepatic insufficiency.

Various diseases, especially those that cause renal or hepatic insufficiency, may alter drug metabolism.

The most common signs are failure to thrive, hepatic insufficiency, cataracts and developmental delay.

In hepatic insufficiency, plasma drug concentrations are significantly affected by concurrent liver disease.

There is currently no information available evaluating the safety of repeated daily ondansetron doses in patients with hepatic insufficiency.

Hepatic insufficiency can be acute or chronic.

Dose adjustment needed if hepatic insufficiency.

Drug dose must be adjusted according to age of patient, and must be lowered in hepatic insufficiency.

Long-term complications of veno-occlusive disease depend on severity but can include hepatic insufficiency or failure and portal hypertension.

ERCC1 knockout mice are runted at birth and die from progressive hepatic insufficiency.

The drug is contraindicated in pregnancy, during lactation, and in patients with severe cardiac, renal or hepatic insufficiency.

It is metabolized in the liver and its action may be prolonged in individuals with hepatic insufficiency (i.e. liver problems).

Ondansetron clearance is diminished in patients with severe hepatic insufficiency; therefore, such patients should receive a single injectable or oral dose no higher than 8 mg.

It is probably contraindicated in patients with hepatic insufficiency and its use should be monitored carefully in patients taking other drugs that alter the normal effectiveness of this metabolic path.

Patients with hepatic insufficiency resulting in serum bilirubin greater than the upper limit of normal (ULN) should not be administered docetaxel, though this is not a stated contraindication.

Hepatic insufficiency implies the inability of the liver to carry out its metabolic, excretory and detoxifying functions owing to a decrease in the number of functional hepatocytes or because their normal activity is altered.

Both types of hepatic insufficiency, ALF and ACLF, can potentially be reversible and liver functionality can return to a level similar to that prior to the insult or precipitating event.

In all reported cases, the initial symptoms included fever, lethargy, anorexia and leukopenia, and quickly progressed to multisystem organ failure, hepatic insufficiency or severe hepatitis, dysfunction of the transplanted organ, coagulopathy, hypoxia, multiplebacteremias and shock.

Dangerous side effects are drug-induced hepatitis and hepatocellular insufficiency.